The CARDIO4Cities approach was validated in three early-adopter cities across three continents: Ulaanbaatar, Mongolia; Dakar, Senegal; and São Paulo, Brazil. In each city, we’ve partnered with authorities to make data-informed decisions for their health systems and populations, tap into emerging technology where appropriate, and inform investments into digital health solutions. These cities have dramatically improved hypertension control rates at population level through the CARDIO4Cities approach.